CellPath^® Tissue Processing/Embedding
Cassettes & Acessories

NEW System II Hex Cassette

The innovative honeycomb design of the Hex Cassette maximizes the open surface area compared to traditional round perforations, increasing reagent flow through for improved processing and a more rigid block when sectioning.

The System II Hex Cassette benefits from an optimized writing surface as well as extra-thick sidewalls that increase stability and rigidity, essential for high-quality sectioning. Supplied loose, threaded (for easy loading of Leica and Sakura printers) or pre-loaded in hopper tubes (for easy loading of Thermo Scientific cassette printers).

System II Hex Cassette can be closed by using the plastic #22101-P or stainless steel #22101-SS lids. These lids are designed specifically for the System II Hex Cassettes.

Key Benefits:

• Hex design maximizes open surface area to increase the fluid exchange
• Optimized writing surface for printing high-quality text, 1D and 2D barcodes
• Writing surface suitable for marking with marker pens and pencil
• A selection of colors available
• Base dimensions: 28.5 x 41 x 6mm

NEW System II Hex Lids

The System II Hex Cassette Lid is compatible with the System II Hex Cassette. Users can choose an easy to attach disposable plastic lid, or a re-useable stainless-steel version depending on their requirements.

Use only the System II Hex Lids with the System II Hex Cassettes.

These lids may not work with Simport and other manufacturers' embedding cassettes.

NEW System III Inkjet Slotted Cassette

The System III Slotted Inkjet Cassette comes with an attached lid with an easy to use frangible (break-off) hinge. With a slotted design, the cassette has a large open surface area to increase reagent flow and improve processing. The locking mechanism of the cassette ensures maximum tissue security during processing.

The cassette has a precisely engineered writing surface which optimizes the print quality on Leica and Sakura printers. It is supplied either loose or threaded for easy loading into the cassette printers.

Key Benefits:

• Compatible with both Leica IPC and Sakura AutoWrite cassette printers
• Optimized writing surface
  
• Increased reagent flow
• Integral fixed frangible lid
  
• High rigidity and stability
  
• A selection of colors available
  
• Base dimensions: 28.5 x 41 x 6mm

NEW System III Thermal Slotted Cassette

The System III Thermal Slotted Cassette comes with an attached lid with an easy to use frangible (break-off) hinge. With a slotted design, the cassette has a large open surface area to increase reagent flow and improve processing. The locking mechanism of the cassette ensures maximum tissue security during processing.

The cassette has a precisely engineered writing surface which optimizes the print quality on Primera printers. It is supplied either loose or threaded for easy loading into the cassette printers.

Key Benefits:

• Compatible with Primera cassette printers
• Optimized writing surface
• Increased reagent flow
• Integral fixed frangible lid
• High rigidity and stability
• A selection of colors available
• Base dimensions: 28.5 x 41 x 6mm

NEW System III Inkjet Biopsy Cassette

The System III Inkjet Biopsy Cassette comes with an attached lid with an easy to use frangible (break-off) hinge. Incorporating square apertures of 0.9mm², the Biopsy Cassette ensures safe accommodation of smaller biopsy specimens, while also enabling fluid exchange. The locking mechanism of the cassette ensures maximum tissue security during processing.

The cassette has a precisely engineered writing surface which optimizes the print quality on Leica IPC/Sakura AutoWrite printers. It is supplied either loose or threaded for easy loading into the cassette printers.

Key Benefits:

• Optimized writing surface for Leica IPC and Sakura AutoWrite cassette printers
• 0.9mm² pore size
  
• Integral fixed frangible lid
  
• High rigidity and stability
  
• Base dimensions: 28.5 x 41 x 6mm

NEW System III Thermal Biopsy Cassette

The System III Thermal Biopsy Cassette comes with an attached lid with an easy to ‘break-off’ hinge. Incorporating square apertures of 0.9mm², the Biopsy Cassette ensures safe accommodation of smaller biopsy specimens, while also enabling fluid exchange. The locking mechanism of the cassette ensures maximum tissue security during processing.

The cassette has a precisely engineered writing surface finish which optimizes the print quality on Primera Signature and Sakura SmartWrite printers. It can be supplied either loose or threaded for easy loading in the cassette printers.

Key Benefits:

• Optimized writing surface for Primera Signature and Sakura SmartWrite cassette printers
• 0.9mm² pore size
  
• Integral fixed frangible lid
  
• High rigidity and stability
  
• A selection of colors available
• Base dimensions: 28.5 x 41 x 6mm

NEW System III Inkjet Micro Biopsy Cassette

The System III Thermal Biopsy Cassette comes with an attached lid with an easy to ‘break-off’ hinge. Incorporating square apertures of 0.38mm², the Biopsy Cassette ensures safe accommodation of smaller biopsy specimens, while also enabling fluid exchange. The locking mechanism of the cassette ensures maximum tissue security during processing.

The cassette has a precisely engineered writing surface finish which optimizes the print quality on Leica IPC and Sakura AutoWrite cassette printers. It can be supplied either loose or threaded for easy loading in the cassette printers.

Key Benefits:

• Optimized writing surface for Leica IPC and Sakura AutoWrite cassette printers
  
• 0.38mm² pore size
  
• Integral fixed frangible lid
  
• High rigidity and stability
  
• A selection of colors available
• Base dimensions: 28.5 x 41 x 6mm

NEW System III Thermal Micro Biopsy Cassette

The System III Thermal Biopsy Cassette comes with an attached lid with an easy to ‘break-off’ hinge. Incorporating square apertures of 0.38mm², the Biopsy Cassette ensures safe accommodation of smaller biopsy specimens, while also enabling fluid exchange. The locking mechanism of the cassette ensures maximum tissue security during processing.

The cassette has a precisely engineered writing surface finish which optimizes the print quality on Primera Signature and Sakura SmartWrite cassette printers. It can be supplied either loose or threaded for easy loading in the cassette printers.

Key Benefits:

• Optimized writing surface for Leica IPC and Sakura AutoWrite cassette printers
  
• 0.38mm² pore size
  
• Integral fixed frangible lid
  
• High rigidity and stability
  
• A selection of colors available
• Base dimensions: 28.5 x 41 x 6mm

Super Mega Hex Cassette

made of acetal polymer

Extra-large processing/embedding cassettes with covers. Disposable cassette designed to hold larger specimens with a maximum thickness of 12mm. Ideal for prostate, brain, breast tissue and eyes. Extremely useful for research and toxicology laboratories.  The new “Hex” pores hold the large tissue specimens to the cassette much more securely than traditional slot design.

Inside dimensions: 64 x 49 x 13mm (2.52" x 1.89" x 0.51")
Outside dimensions: 75 x 52 x 17mm (2.95" x 2.05" x 0.71")

Use with 27197, 27197-1 and 27197-2 Super Mega Cassette Stainless Steel Base Molds

Super Mega Mothership Cassette

made of acetal polymer

With an internal cavity a third of the depth of the conventional Super Mega, the Super Mega Mother Ship provides an innovative solution for the processing and embedding of large tissue specimens.

Using this cassette helps meet recommendations for HER2 testing in the UK and ASCO/CAP in the USA. By reducing specimen thickness (5mm or less), processing time is shortened while ensuring high quality tissue processing.

The Super Mega Mother Ship cassette uses an innovative permanent docking bay for a standard tissue processing cassette printed with ID barcodes and/or test information. This enables the specimen to be entered onto a LIMS guaranteeing its accurate and reliable tracking. 100 printable cassettes are provided with each box of 100 Super Mega Mothership Cassettes. Casting can be done in 30 minutes at -8°C. Available in 7 colors.

Inside dimensions: 64 x 50 x 5mm (2.52 x 1.89 x 0.51")
Outside dimensions: 75 x 52 x 17mm (2.95 x 2.05 x 0.71")

Use with 27197-4 Super Mega Stainless Steel Base Mold

Super Mega Hex Slim Cassette

made of acetal polymer

Extra-large processing/embedding cassettes with covers. Disposable cassette designed to hold larger specimens with a maximum thickness of 5mm. Ideal for prostate, brain, breast tissue and eyes. Extremely useful for research and toxicology laboratories. Optimal for large specimens grossed at 5mm thickness for improved fixation and tissue processing.

Inside dimensions: 64 x 50 x 5mm (2.52" x 1.89" x 0.51")
Outside dimensions: 75 x 52 x 7mm (2.95" x 2.05" x 0.71")

Use with 27197-3 Super Mega Cassette Stainless Steel Base Mold

Spacer Bar for Super Mega Hex Slim Cassettes

The Super Mega Slim Cassette Spacer Bar is to be used with the Super Mega Slim Cassette when sectioning. The adapter bar fits the back side of an embedded Super Mega Slim paraffin block. When pre-chilled, the spacer bar will also provide additional cooling to the block during sectioning.

Use with 27199 Super Mega Hex Slim Cassettes

Super Mega Universal Cassette Clamp for Microtomes

Universal Super Mega Cassette Clamp is used during the microtomy of large tissue blocks.

Incorporating an intuitive quick-release system, the clamp can securely hold any tissue processing cassette from the Super Mega series of cassettes.

• Compatible with Leica Biosystems RM 2100 & RM 2200 and Microm HM Series of microtomes” (70mm vertical stroke)
• Secure Clamping of Super Mega Cassettes
• Quick release function saves time
• Unique design avoids collision between the clamp and microtome knife holder
• Highly durable, manufactured from aluminum

Use with Super Mega Hex Cassettes, and Super Mega Hex Slim Cassettes with 27199 Spacer Bar

CellSafe™ 5 Five Chamber Biopsy Cassettes

• Small needle core tissue specimens may be processed separately
• Ideal for breast and prostate core biopsies
• 200 x 200 micron nylon mesh screen top and bottom
• X-ray transparent fine mesh
• Available in white and blue

The CellSafe™ is designed to contain small tissue fragments and biopsies during tissue processing. The CellSafe™ 5 was developed for the simultaneous preparation of core biopsies, ideal for breast and prostate specimens. Each well is numbered for identification. The blue cassette aids contrast and visualization of light colored biopsies, normally experienced with breast tissue.

The acetyl resin frame and nylon mesh are suitable for use in common tissue processing reagents including Formaldehyde solutions, Bouin's Fluid, Alcohol solutions, Xylene, Chloroform, Citrus based clearing agents and Paraffin wax (melting point up to 65°C). If you are using any unusual reagents it is suggested that you carry out preliminary chemical compatibility tests before using the CellSafe™ 5 to contain tissue samples.

CellSafe™ + Biopsy Capsules shown
open and closed & inserted into a
regular tissue cassette.

CellSafe™ + Biopsy Capsules v2

The CellSafe™ + Biopsy Capsule is designed to contain small tissue fragments and biopsies during tissue processing. The blue CellSafe™ + Biopsy Capsule makes it easier to see small pieces of tissue contrasting with the blue mesh screen. The CellSafe™ + Biopsy Capsule with a hinged cover fits into a regular cassette. Top and bottom consist of extra fine nylon mesh, 200 x 200 micron mesh screen, preventing small tissues from getting lost during specimen preparation, keeping them safe. The plastic frame and nylon mesh are suitable for use in common tissue processing reagents including formaldehyde solutions, Bouin's fluid, alcohol solutions, xylene, chloroform, citrus-based clearing agents and paraffin wax (melting point up to 65°C). The plastic frame is made from the same material widely used in the manufacture of plastic processing cassettes. If you are using any unusual reagents it is suggested that you carry out preliminary chemical compatibility tests before using the CellSafe™ + Biopsy Capsule to contain tissue samples. The CellSafe™ + Biopsy Capsule is designed for single use only.

Interior dimensions of a regular cassette are: 30 x 26 x 4.92mm H.
Exterior dimensions of the CellSafe™ + Biopsy Capsule are: 27.5 x 25 x 4.57mm H.

NEW Curetting Cassette Stainless Steel Insert and Lid

The Curetting Cassette with Stainless Steel Insert and Lid is designed to prevent the loss of a small specimen sample while allowing excellent fluid exchange.

Embedding Rings

made of high impact polystyrene

Embedding rings are suitable for holding and identifying tissue sample blocks and fit well in microtome chuck adapters. The etched writing surface on the ring is marked with an identification number and placed on top of the sample block. Additional paraffin is poured into the base mold to cement the ring onto the tissue block. The embedding ring securely holds the tissue sample in the microtome chuck adapter for sectioning and then identifies the sample while in storage. Embedding rings are available in white. Sold in boxes of 250 rings; one case is four boxes of 250 rings.

Use with #27147-6 Disposable Deep Base Mold

Use with #27190 through 27196 Stainless Steel Base Mold

Biopsy Foam Sponge Pads

made of polyester urethane foam

Biopsy Foam Sponge Pads prevent tissues from being lost during processing. Made of cellular polyester urethane foam which is always verified for consistency throughout in order to achieve optimum solvent flow. Biopsy samples are sandwiched between two foam pads and are placed in tissue cassettes/capsules with metal or plastic lids. Packed 1000 per bag.

1 Case is 10 packages of 1000.

Biopsy Bags