Neuroscience Products Overview

Introducing a NEW STANDARD in tissue slicing.

PELCO easiSlicer™   EB+GFAP+DAPI - 50μm - P. Nahirney Affordable Quality.
A fresh approach to traditional standards, the PELCO easiSlicer™ brings precision vibratory tissue slicing to labs of all sizes.
  Cresyl Violet 50μm - C. Meshul - Portland VAMC Consistent Reliability.
Solid construction and exceptional stability provides exacting control of section thickness with minimal z-axis vibration.
  EB+GFAP+DAPI - 50μm - P. Nahirney Simple Versatility.
Simple, effective, manual design makes the PELCO easiSlicer™ perfect for multi-user and multi-application labs.
  EB+GFAP+DAPI - 50μm (Top/Bottom) - P. Nahirney - UVic, B.C.; Cresyl Violet 50μm (Center) - C. Meshul - Portland VAMC

The PELCO easiSlicer™ introduces a new standard in vibratory slicing. It combines ease of operation, precise engineering and affordable pricing in a high quality instrument. The PELCO easiSlicer™ uses rigid construction and advanced engineering technologies to essentially eliminate backlash resulting in minimal Z-axis vibration normally associated with more expensive vibratory slicers. All operational controls are located on the front of the instrument, clearly labeled and sealed against moisture. The specimen tray is held securely in the polypropylene bath by a set of strong magnets. The bath is attached from the side with a unique spring-loaded base that locks onto the PELCO easiSlicer™ by simple pressure. The integrated bath and tray design allows them to move as a unit for sectioning thickness or height adjustment. The bath and tray can be easily separated for simple and fast clean-up, eliminating the risk of leaks and a cumbersome drain or hose.

The amplitude and speed controls are conveniently mounted in the center of the control panel for ease of operation. The instrument is supplied with a newly designed lever tightening blade holder set at a 15° cutting angle that accepts all knife thicknesses from Feather® blades to the thick Sapphire blade. Also available are blade holders for Feather® blades offered in two fixed cutting angles: 18° and 21°. The specialized design of these blade holders provides a secure and rigid grasp of the cutting blade. Feather® Blades are recommended for use with these 18° and 21° fixed cutting angle blade holders. The fixed cutting angle blade holders will accommodate other types of blades, but will not accept a Sapphire blade. The Sectioning Window Controls guide the user for precise cutting window control with indicator lights on the control panel.

The Magnifier and Light Assembly offers bright white LED lighting (no risk of high temperatures) with high or low settings, depending on the user’s need. The Magnifier can be moved out of the viewing path, if desired. The entire assembly operates smoothly on metal slides.

The large Section Thickness Knob is centrally located in the work area. The knob is labeled in microns and has a perceptible detent every 5 microns. One complete revolution of the knob is 100 microns. The entire bath and tray assembly is raised and lowered by this Section Thickness Knob. The PELCO easiSlicer™ has a Return Switch that provides the user with an option for Auto Return after each slice. In the Manual Return mode, the cutting will cease once the end of the section window has been reached. This allows the retraction of the specimen before the return of the blade in order to prevent damage to the specimen.

The PELCO easiSlicer™ comes equipped with tools and supplies to start cutting quality, consistent sections, right out of the box.

PELCO easiSlicer™ Product Intro

Features & Benefits

  • Precision design for accurate, high quality sections with minimal z-axis vibration
  • Novel bath design utilizes unique easy-locking base making it simple to clean
  • Anodized specimen tray magnetically locks onto bath
  • Optional magnetic base for tissue mounts available
  • Cuts sections down to 20 microns
  • LED lights indicate active vibratory status and cutting window boundaries
  • Adjustable Blade Holder utilizes compression lever release and tightening, 15º cutting angle. Securely holds the thinnest Feather® blades to a Sapphire Blade.
  • Optional Removable Blade Holders available for Feather® blades at 18º and 21º preset angles.
  • Fully assembled, ready to use
  • Affordable pricing
  • Universal power supply 100-240V, 50/60Hz

PELCO easiSlicer™ Tray and Bath Novel Bath (#11010) design utilizes unique easy-locking base for secure and simple attachment; no risk of fluid leaking into the instrument.
PELCO easiSlicer™ Magnifier LED Light Magnifier/LED Light Assembly avoids risk of high temperature, offers 2X magnification and convenient, smooth operation.
PELCO easiSlicer™ Removable Blade Holder NEW Removable Blade Holder (#11051-15) with innovative lever release and tightening of blades for easy knife exchange. Securely holds blades at a 15º cutting angle. Will hold most all blades for vibratory slicers from the thinnest Feather® blades to the Sapphire knife/blade.
PELCO easiSlicer™ Removable Blade Holder Optional Removable Blade Holders with innovative tooling for secure and rigid hold of Feather® blades at 18º (#11050-18) and 21º (#11050-21) angles.
PELCO easiSlicer™ Removable Blade Holder Convenient Blade Holder Rest (#11055) facilitates easy blade exchange.

Optional base for tissue mounts (11014) magnetically locks into bath in place of specimen tray as shown.   Four sizes of engraved tissue mounts available.

All operational controls are located on the front of the PELCO easiSlicer™, clearly labeled and sealed against moisture. Easily visible LED lights indicate active vibratory status, an exclusive safety feature, and cutting window boundaries.

PELCO easiSlicer™ Specifications

Maximum Specimen Size
40 x 40mm (1.58 x 1.58")
Maximum Specimen Height
15mm (0.6")
Specimen Bath
Spring-loaded; polypropylene
Specimen Tray
Rectangular with magnet release.
Blade Type
Feather® blades recommended
Blade Angle
15° standard; 18°, 21° available
Sectioning Window
10 - 40mm (0.4 - 1.58")
Specimen Height Adjustment (Z-Axis)
15mm (0.59") total travel in 1μm increments; tactile click stops at 5μm
Cutting Arm Speed (Y-Axis)
Forward: 0 - 2.0mm/sec (0 - 0.08"/sec)
Reverse: 5mm/sec (0.2"/sec)
Travel: 40mm (1.58”) total
Vibratory Amplitude (X-Axis)
0 - 1.00mm (0.04") total; continuously adjustable
Cutting Arm Frequency
50Hz ±5 factory set
2X magnifier
LED illumination; LOW/OFF/HIGH
535 x 300 x 290mm (21.1 x 11.8 x 11.4")
16.8 kg (37lbs)
Utility Requirements
100 - 240V; 50/60 Hz; 345VA

PELCO easiSlicer™ Cutting Windows

PELCO easiSlicer™ Dial

PELCO easiSlicer™ Magnifier

Product Video

Ordering Information for the PELCO easiSlicer™

Manufactured in USA

Prod # Description Unit Price Order / Quote
11000 PELCO easiSlicer™ Vibratory Tissue Slicer each P.O.R.
Included Accessories: 1 Black Anodized Tray (11020); 1 Bath (11010); 1 Lever Release Blade Holder 15° (11051-15); 1 Box of 10 Feather® Blades (121-9); 1 PELCO® Pro Specimen Retriever (101-33); 1 Bottle PELCO® Pro CA44 Tissue Adhesive, 20ml (10033); 1 PELCO easiSlicer™ Dust Cover (11060); 1 PELCO easiSlicer™ Blade Holder Rest (11055); 1 Set of Camel's Hair Brushes (11870); 1 Replacement Fuse (030-758)

PELCO easiSlicer™ Accessories

Prod # Description Unit Price Order / Quote
11010 PELCO easiSlicer™ Bath each $275.00
11012 PELCO easiSlicer™ Magnetic Base for Tray each 127.50
11020 PELCO easiSlicer™ Black Anodized Tray each 194.50
11022 PELCO easiSlicer™ Blue Anodized Tray each 194.50
11014 PELCO easiSlicer™ Magnetic Base for Tissue Mounts each 127.50
11051-15 NEW PELCO easiSlicer™ Blade Holder 15°, Lever Release each 385.00
11050-18 PELCO easiSlicer™ Blade Holder 18° each 385.00
11050-21 PELCO easiSlicer™, Blade Holder 21° each 385.00
11052 PELCO easiSlicer™ Hex Driver for Blade Holder each 8.25
11055 PELCO easiSlicer™ Blade Holder Rest each 97.50
11060 PELCO easiSlicer™ Dust Cover each 33.25
101-33 PELCO® Pro Specimen Retrievers pkg/5 75.10

Prod # Description Unit Qty Price Order / Quote
11030 PELCO easiSlicer™ Engraved Tissue Mounts Mixed-pak:(2ea) 25mm, (2ea) 32mm, (2ea) 38mm and (2ea) 50mm pkg 1+ $99.50
11031 PELCO easiSlicer™ Engraved Tissue Mount, 25mm each 1-4 8.00
5+ 7.50
11032 PELCO easiSlicer™ Engraved Tissue Mount, 32mm each 1-4 9.50
5+ 9.00
11033 PELCO easiSlicer™ Engraved Tissue Mount, 38mm each 1-4 12.50
5+ 12.00
11034 PELCO easiSlicer™ Engraved Tissue Mount, 50mm each 1-4 18.20
5+ 17.70

Related Products

Feather Razor Blade for Vibratome use

Feather® Blades

Carbon steel; sharp edges. Break in half lengthwise for use (protect fingers and use eye protection). This is the preferred cutting blade for use with the PELCO easiSlicer™. Ideally suited for use with Microslicer™, Vibratome® and other vibratory slicers. Excellent when used as is (unbroken) in McIlwain Tissue Chopper.
• Length: 42.8mm (1.685")
• Cutting Edge Length: 36mm (1.42")
• Width: 22mm (0.865")
• Thickness: 0.127mm (0.0045")

Prod # Description Unit Price Order / Quote
121-9 Feather® Double Edge Carbon Steel Blades pkg/10 $12.50

Specimen Retrievers

PELCO® Pro Specimen Retrievers

This is a perfect tool for retrieving free floating sections from the bath. Made of glass.

Prod # Description Unit Price Order / Quote
101-33 PELCO® Pro Specimen Retrievers pkg/5 $75.10

PELCO Pro CA44 Tissue Adhesive

PELCO® Pro CA44 Tissue Adhesive

PELCO® Pro CA44 is an instant tissue adhesive based on cyanoacrylate. Developed to glue tissue on specimen holders used in vibratory microtomes. Although the tissue adhesive is instable in boiling water, it is recommended to use #19920 PELCO® Pro Cyanoacrylate Debonder to remove or clean cured cyanoacrylate. Supplied in 20ml bottle with dispenser tip, closed with PTFE coated steel pin for optimum seal. Comparable to Loctite 404 tissue adhesive.

I - SDS (213KB PDF)


Prod # Description Unit Price Order / Quote
10033 PELCO® Pro CA44 Instant Tissue Adhesive, 20ml each $10.10

Camel's Hair Brushes
camel hair brush

Camel Hair Brushes

Useful for histology section manipulation, SEM, geology, forensic. Seamless ferrules, red enameled handles. #6 brush for larger brushing work on specimens. Measurements taken just above ferrule.

Prod # Description Unit Price Order / Quote
11859 Camel Hair Brushes, #1, less than 1.59mm wide pkg/3 $14.90
11860 Camel Hair Brushes, #2, 1.59mm wide pkg/3 23.10
11862 Camel Hair Brushes, #4, 3.18mm wide pkg/3 27.50
11870 Camel Hair Brushes, Multi Pack of 3 Brushes, #1, #2, #4 pkg/3 20.10
11878 Camel Hair Brush, #6, 3.18mm wide pkg/3 36.10

Red Sable Brushes

Red Sable Brushes

For precise manipulation of TEM specimen grids and samples, dusting of SEM samples and photographic materials or photographic spotting. Sable hairs are springy and relatively fine. Length of hairs are short for better manipulation. Enameled wood handles and seamless nickel ferrules. Offered in packages of 3 brushes. Measurements taken just above ferrule.

Prod # Description Unit Price Order / Quote
11806 Sable Brushes, #00000, 0.08mm W x 4.0mm L pkg/3 $15.70
11807 Sable Brushes, #000, 1.0mm W x 6.0mm L pkg/3 16.80
11808 Sable Brushes, #00, 1.0mm W x 7.0mm L pkg/3 17.60
11810 Sable Brushes, #0, 1.3mm W x 8.0mm L pkg/3 20.90
11812 Sable Brushes, #1, 1.5mm W x 9.5mm L pkg/3 19.30
11814 Sable Brushes, #2, 1.8mm W x 11.5mm L pkg/3 23.10
11816 Sable Brushes, #3, 2.0mm W x 13.0mm L pkg/3 25.30

eyelash with handle

Camel Hair Brush

Full Body Camel Hair Brush secured by a crimped metal ferrule.

Ideal for cleaning cryostats and microtomes of debris and dust. Overall length 22.86cm (9").

Prod # Description Unit Price Order / Quote
11872 Camel Hair Brush, 1.91cm (3/4") W x 3.81cm (1-1/2") L each $7.00

tissue culture plate36168-6 6-Cavity
Tissue Culture Plate
tissue culture plate36170-12 12-Cavity
Tissue Culture Plate
tissue culture plate36172-24 24-Cavity
Tissue Culture Plate

Corning Costar® Tissue Culture Plates

Tissue Culture-treated Plates are designed for a wide range of applications including general cell growth experiments, cloning studies, virus isolation and in vitro testing.

Plate bottoms have a uniform thickness, allowing for distortion-free observation. Alphanumeric coordinates are placed on the same focal plane as cell growth, for convenient referencing of cell position. Gripping edges make handling easier.

All plates have non-reversible covers with condensation rings to minimize evaporation and the risk of contamination.

Plates are made of optically clear, medical-grade non-pyrogenic polystyrene, TC-treated, sterile and are used for processing of tissue on the bench or in the microwave. The corresponding Wellplate Inserts are No. 36168 for the 6 cavity, No. 36170 for the 12 cavity, and No. 36172 for the 24 cavity.

of Wells
36168-6 6 35mm 9.5cm2 15ml 2-3ml
36170-12 12 22.6mm 3.8cm2 7ml 1ml
36172-24 24 16mm 1.9cm2 3.4ml 0.5ml

Prod # Description Unit Price Order / Quote
36168-6 Tissue Culture Plate, 6 wells pkg/10 $54.00
36170-12 Tissue Culture Plate, 12 wells pkg/10 62.70
36172-24 Tissue Culture Plate, 24 wells pkg/10 69.50


SecureSeal™ Sealing Film

SecureSeal™ is a thermal adhesive sealing film which consists of 2.0 mil polyolefin film coated on one side with pressure sensitive acrylate adhesive. Designed to reduce spill-over and well to well contamination in tissue culture plates, SecureSeal™ also minimizes evaporation and vapor loss for PCR applications.

This film has low autofluorescence and is functional from -70°C to +100°C. Certified RNase, DNase and DNA-free; DMSO resistant. Available in sterile and non-sterile packages.

Prod # Description Unit Price Order / Quote
36167-1 SecureSeal™ Sealing Film pkg/100 $99.00
36167-2 SecureSeal™ Sealing Film Sterile pkg/100 112.00

individual wells for specimen processing

Amplate™ Roller

Roller made of medium hard rubber secured in a heavy duty handle.

Manufactured with a comfort grip to assist in creating a perfect seal when used with SecureSeal™ Sealing Film.

Prod # Description Unit Price Order / Quote
36167 Amplate™ Roller each $39.25

PELCO Prep-Eze™ Wellplate Inserts

The rectangular polypropylene Wellplate Inserts have 6, 12, or 24 wells and will fit into the Corning Costar® Tissue Culture Plates of 6/12/24 Wellplate design. A 420µm opening, polypropylene mesh is at the bottom of each of the insert wells.

The Wellplate Inserts may only be chemically sterilized.

The outside dimensions of the Wellplate Inserts are: 81.3mm W x 123.5mm L x 24mm H (3.2" W x 4.86" L x 0.88" H)

Well dim. of 6-wellplate inserts: 24.1mm dia x 22.3mm D (0.95" dia x 0.88" D)
Well dim. of 12-wellplate inserts: 14.2mm dia x 22.3mm D (0.56" dia x 0.88" D)
Well dim. of 24-wellplate inserts: 11.2mm dia x 22.3mm D (0.44" dia x 0.88" D)
Depth of well from top to bottom on all Wellplate Inserts: 17.68mm (0.696")

Prod # Description Unit Price Order / Quote
36168 PELCO Prep-Eze™ 6-wellplate Insert each $105.20
36170 PELCO Prep-Eze™ 12-wellplate Insert each 145.20
36172 PELCO Prep-Eze™ 24-wellplate Insert each 243.00
36168-8 6-well Insert (or 24.1mm dia.) Replacement Mesh, 420µm pkg/30 31.40
36170-14 12-well Insert (or 14.2mm dia.) Replacement Mesh, 420µm pkg/36 31.40
36170-24 24-well Insert (or 11.2mm dia.) Replacement Mesh, 420µm pkg/48 38.00

For Individual Wells, click here

PELCO® Technical Notes, PELCO Prep-Eze™ Rectangular Wellplate Inserts - Instructions (PDF File)

individual wells for specimen processing

8-Section Staining Nets

Dimensions: 3-1/2" diameter x 1-1/2" high (89 x 38mm). Available with netting of 32 mesh (left) or 64 mesh (right, shown in Staining Dish 36754-60). Rod in center of net can be grasped to lift net from Staining Dish.

Prod # Description Unit Price Order / Quote
36154-32 8-Section Staining Net, 32 mesh each $107.25
36154-64 8-Section Staining Net, 64 mesh each 107.25