Material Safety Data Sheet

Product No. 19479, 19480 Histomount™                             

Issue Date (04-27-01)

Review Date (03-06-07)

Section 1: Product and Company Identification

Product Name: Histomount™

Synonym: Chemical names: Aromatic hydrocarbons

Company Name

Ted Pella, Inc. and PELCO International, P.O. Box 492477, Redding, CA 96049-2477
Domestic Phone  (800) 247-3526 (Mon-Thu. 6:00AM to 4:30PM PST; Fri 6:00AM to 4:00PM PST)

International Phone (01) (530) 243-2200 (Mon-Thu. 6:00AM to 4:30PM PST; Fri 6:00AM to 4:00PM PST)

Chemtrec Emergency Number 1-800-424-9300 24 hrs a day.

Section 2: Composition / Information on Ingredients

Principle Hazardous Component(s) (chemical and common name(s)) (Cas. No)	%	OSHA PEL PPM	ACGIH  TLV   PPM	NTP	IARC	OSHA regulated
Xylenes, Mixed Isomers(1330-20-7)	30-50	100	100	No	3	NIF
Non-hazardous Components	40-60	ND	ND	No	None	ND

Section 3: Hazard Identification
Emergency overview

Appearance: Clear, colorless liquid.

Immediate effects: Danger! Harmful or fatal if swallowed. Vapor harmful. Affects central nervous system. Causes severe eye irritation. Causes irritation to skin and respiratory tract. May be harmful if absorbed through skin. Flammable liquid and vapor.

Chronic hazard warning: Acute or chronic overexposure to this material or its components may cause systemic toxicity including adverse effects to the following: kidney, liver, brain, blood, spleen, testes, fetus and central nervous system.

Potential health effects

Primary Routes of entry: Inhalation, ingestion, skin contact.

Eyes: Vapors cause eye irritation. Splashes cause severe irritation, possible corneal burns and eye damage.

Skin: Skin contact results in loss of natural oils and often results in a characteristic dermatitis. May be absorbed through the skin.

Ingestion: May cause irritation of the mouth, throat, and gastrointestinal tract. Aspiration into lungs may cause chemical pneumonia and lung damage.

Inhalation: Inhalation of vapors may be irritating to the nose and throat. High vapor concentrations are anesthetic and central nervous system depressants.

Signs and Symptoms of Overexposure

Inhalation: Inhalation of high concentrations may result in nausea, vomiting, headache, ringing in the ears, and severe breathing difficulties which may be delayed in onset. Substantial pain, cough, and hoarseness are also reported. Symptoms of central nervous system depression or effects which may occur can include headache, excitation, euphoria, dizziness, in-coordination, drowsiness, light-headedness, blurred vision, fatigue, tremors, convulsions, loss of consciousness, coma, respiratory arrest and death, depending on the concentration and duration of exposure.

Ingestion: Salivation, pain, nausea, vomiting and diarrhea. Exposure may also cause central nervous system symptoms similar to those listed under "Inhalation."

Skin: Reddening, itching, and inflammation. Repeated or prolonged contact may result in drying, reddening, itching, pain, inflammation, cracking and possible secondary infection with tissue damage.

Eyes: Pain, tears, burns, sensitivity to light, swelling and possible corneal damage. Prolonged or repeated exposure may cause irritation and conjunctivitis.

Chemical Listed As Carcinogen Or Potential Carcinogen: IARC has determined that there is inadequate evidence to assign the carcinogenicity of Xylenes in humans and in experimental animals (IARC Class 3).

See Toxicological Information (Section11)

Potential environmental effects

See Ecological Information (Section 12)

Section 4: First Aid Measures
If accidental overexposure is suspected

Eye(s) Contact: Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion: Do not induce vomiting. If Swallowed and the person is conscious, immediately give large amounts of water. Get medical attention.

Note to physician

Treatment: ND

Medical Conditions generally Aggravated by Exposure: Target organ statement. Pre-existing medical conditions which may be aggravated by exposure include disorders of the skin, eye, heart, kidney, liver, and blood, and respiratory system, neurological and hematopoietic organs.

Section 5: Fire Fighting Measures
Flash Point: 29 °C (84 °F)
Flammable Limits: LEL: 1.0%; UEL: 7.0%

Auto-ignition point: 464 °C (867 °F)
Fire Extinguishing Media: Dry powder, foam, carbon dioxide. Water spray may be used to keep fire exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.

Special Fire Fighting Procedures: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.

Unusual Fire and Explosion Hazards: Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Contact with strong oxidizers may cause fire. Sealed containers may rupture when heated. Sensitive to static discharge.

Hazardous combustion products: Involvement in a fire causes formation of carbon monoxide and unidentified organic components.

DOT Class: 3 (Flammable liquid)

Section 6: Accidental Release Measures
Steps to be Taken in Case Material is Released or Spilled: Ventilate area of leak or spill. Remove all sources of ignition. Isolate hazard area. Collect liquid in an appropriate container or absorb with an inert material and place in a chemical waste container. Do not flush to sewer! Wear appropriate protective equipment as specified in section 8.

Waste Disposal Methods: Dispose of waste according to Federal, State and Local Regulations.

Section 7: Handling and Storage
Precautions to be Taken in Handling and Storage: Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Transfer methods should avoid static sparks. Use explosion proof ventilation. Keep in a tightly closed container, stored in a cooled, dry, ventilated area away from sources of heat or ignition. Protect from physical damage. Isolate from incompatible materials (section 10).

Storage temperature: Room Temperature.

Storage Pressure: ND

Section 8: Exposure Controls / Personal Protection
Engineering Controls

Ventilation required: A system of local and/or general exhaust is recommended to keep employee exposures below the Air born Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source. See section 2.

Personal Protection Equipment

Respiratory protection: If the exposure limit is exceeded, wear a supplied air, full-face piece respirator, air lined hood, or full-face piece self-contained breathing apparatus.

Protective gloves: Wear impervious gloves.
Skin protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.

Additional clothing and/or equipment: NIF

Exposure Guidelines

See Composition/Information on Ingredients (Section2)

Section 9 Physical and Chemical Properties
Appearance and Physical State: Clear, colorless liquid

Odor (threshold): Slight sweet odor.

Specific Gravity (H2O=1): 0.95

Vapor Pressure (mm Hg): 4 @ 25 °C

Vapor Density (air=1): 4.8

Percent Volatile by volume: 60

Evaporation Rate (butyl acetate=1): 0.7

Boiling Point: 137-140 °C

Freezing point / melting point: -25 °C
pH: NA
Solubility in Water: Insoluble.
Molecular Weight: NA, mixture.

Section 10: Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.

Materials to Avoid (Incompatibility):  Xylene, Mixed Isomers, Strong oxidizing agents and strong acids.
Hazardous Decomposition Products: Involvement in fire causes formation of carbon monoxide and unidentified organic compounds.

Hazardous Polymerization: Will not occur.

Section 11: Toxicological Information

Results of component toxicity test performed: Product LD50 Values: Histomount, Oral, Rat LD50: 10750 mg/kg, Dermal, Rabbit LD50: 4250 mg/kg

Mutagenicity: Has been shown to be positive in mutagenicity.

Reproductive Toxicity: May cause adverse reproductive and/or developmental effects. Pregnant women may be at an increased risk from exposure. Consumption of alcoholic beverages may enhance toxic effects.

Teratogenic Effects: May cause teratogenic effects.

Human experience: NIF

This product does not contain any compounds listed by NTP or IARC or regulated by OSHA as a carcinogen.

Section 12: Ecological Information

Ecological Information and Chemical Fate Information: Xylenes, Mixed Isomers

When released into the soil, this material may evaporate to a moderate extent. When released into the soil, this material is expected to leach into groundwater, when released into the soil, this material may biodegrade to a moderate extent. When released into water, this material may evaporate to a moderate extent. When released into water, this material may biodegrade to a moderate extent. When released into the air, this material may be moderately degraded by reaction with photo chemically produced hydroxyl radicals. When released into the air, this material is expected to have a half-life of less than 1 day. This material is not expected to significantly bio-accumulate (mixed Xylenes: octanol/water partition coefficient 3.1 - 3.2; bio-concentration factor - 1.3 eels). This material is expected to be slightly toxic to aquatic life. The LC50/96-hour values for fish are between 10 and 100 mg/l.

Non-hazardous Component: NIF

Section 13 Disposal Considerations

RCRA 40 CFR 261 Classification: NIF for mixture. Observe all national, state and local regulations regarding disposal.

Federal, State and local laws governing disposal of materials can differ. Ensure proper disposal compliance with proper authorities before disposal.

Section 14: Transportation Information

US DOT Information: Proper shipping name: Xylenes

Hazard Class: 3

Packaging group: III

UN Number: UN1307

Limitations: RQ Xylenes, 100 lbs, 45.4 Kg

IATA: Proper shipping name: Xylenes

Hazard Class: 3

Packing group: III

UN Number: UN1307

Limitations: ND

Domestic shipments only: ND

IMO: Proper shipping name: Xylenes

Class: 3

UN Number: UN1307

Packing group: III

EMS: ND

MFAG: ND

Marine Pollutant: ND

Canadian TDG: Proper shipping name: Xylenes

IMDG Page: ND

Limitations: ND

Section 15: Regulatory Information

United States Federal Regulations

MSDS complies with OSHA’s Hazard Communication Rule 29, CFR 1910.1200.

SARA: 311/312 Hazard Categories

Component: Xylenes, Mixed Isomers: Fire, Yes; Pressure, No; Reactivity, No; Acute, Yes; Chronic, Yes.

Component: Non-hazardous: Fire; No; Pressure, No; Reactivity, No; Acute, No; Chronic, No.

RCRA: NIF

TSCA: All intentional ingredients are listed on the TSCA Inventory.

CERCLA: Mixed Xylenes: RQ 100 lbs (45.4 Kg)

State Regulations

California Proposition 65: Warning: This product contains chemical(s) known to the state of California to cause cancer and birth defects or other reproductive harm. Ethylbenzene and Benzene.

International Regulations

Canada WHMIS: NIF

Europe EINECS Numbers: 215-535-7

Section 16: Other Information

Label Information: Harmful

European Risk and Safety Phrases: R: 10-20/21-38, Flammable. Harmful by inhalation and in contact with skin. Irritating to the skin.

S: (2-) 25, Keep out of reach of children. Avoid contact with the eyes.

European symbols needed: X - Harmful

Canadian WHMIS Symbols: NIF

NFPA Hazard Rating: Health: 2; Flammability: 3; Reactivity: 0

(0=least, 1=Slight, 2=Moderate, 3=High, 4=Extreme)

Abbreviations used in this document

NE= Not established

NA= Not applicable

NIF= No Information Found

ND= No Data

Disclaimer
Ted Pella, Inc. makes no warranty of any kind regarding the information furnished herein. Users should independently determine the suitability and completeness of information from all sources. While this data is presented in good faith and believed to be accurate, it should be considered only as a supplement to other information gathered by the user. It is the User's responsibility to assure the proper use and disposal of these materials as well as the safety and health of all personnel who may work with or otherwise come in contact with these materials.

 

MSDS Form 0013F1 V2