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McIlwain Tissue Chopper
Ideal Micro-Drill™ and Burrs

Improved Microslicers™ and new LinearSlicer™ PRO7
for Sectioning Fresh or Fixed Tissue

Microslicer™ DTK-1000 Microslicer™ DTK-Zero1
LinearSlicer PRO7
Microslicer™ DTK-3000W LinearSlicer™ PRO7

The DTK Microslicers™ have a unique design for the vibratory motion of the cutting blade. They are made to cut sections of extremely soft tissues like brain, liver or similar difficult-to-section material. The Microslicers™ line of instruments are well known for their quality and their superior results, enjoying an excellent reputation in the neuroscience research community.

Objective of the Microslicer™

The Microslicer™ is an instrument used to cut sections of fresh or fixed animal or plant tissues without freezing the tissues.

Fresh tissue sections (10 to 500 micrometers in thickness) are used in anatomy, physiology and pharmacology research areas. In addition, fresh botanical tissue sections are also used in the various research fields.

Histochemistry and cytochemistry procedures require incubation of tissue sections in various reaction media. Large tissue blocks and thick tissue sections often produce non-specific deposits of reaction products and areas of no reaction in the center of the tissues. This is due to the poor penetration of the reaction media into the tissue. The use of thinner tissue sections is required to facilitate the penetration of the reaction medium into the tissues.

DSK Microslicer™ (DTK-1000, DTK-Zero1 and DTK-3000W) are instruments for cutting non-frozen tissue sections easily and efficiently.

There is a Choice of Three Microslicer™ Models and the New LinearSlicer™ PRO7:

The Microslicer™ vibrating tissue slicer system feature a constant cutting amplitude and a selectable frequency. The DTK-Zero1, and DTK-3000W models feature the Microslicer™ Zero-Z technology with a redesigned cutting head for dramatically reduced Z-axis vibration. All systems have a bath with a simple but effective drain. The specimen tray allow for reduced use of solutions and cooling around it. The layout of the switches on either side of the tray allows for easy operation and reduced spillage on the controls.

Applications: Neuroscience Research, Physiology, Immunocytochemistry, Pharmacology, Pathology, Fluorescent Antibody Study, Histology, Cytology

Journal References to Research Work Done Using a Microslicer™

Microslicer™ Accessories and Consumables


microslicer dtk-1000

Microslicer™ DTK-1000

A high quality, basic vibrating microtome, suitable for a busy laboratory, with many users.

Functions Include:

  1. Frequency dial
  2. Cutting speed dial
  3. Function switch; reverse; stop; forward
  4. Lamp switch
  5. Main switch
  6. Section thickness knob
  7. Motor box
  8. Blade holder
  9. Buffer tray
  10. Magnifier assembly with fluorescent lamp

Ordering Information
Prod #DescriptionUnitPriceOrder / Quote
10000
Microslicer™ DTK-1000, 120V, 60Hz
each
P.O.R.
Qty:
10000-220
Microslicer™ DTK-1000, 220V, 50/60Hz
each
P.O.R.
Qty:




Microslicer™ DTK-Zero1

New Microslicer™ DTK-Zero1

the first tissue sectioning equipment with Zero "Z" technology

This model Microslicer™ with Zero Z technology dramatically reduces the Z-axis vibrations to approximately 2.5 microns. It is also equipped with a specimen retraction system. The specimen advance is manual but the specimen can be moved up or down by a motorized button. A function switch can stop, advance or retract the cutting action, saving valuable time.

  Functions Include:
 

1. Frequency dial
2. Cutting speed dial
3. Function switch; reverse; stop; forward
4. Lamp switch
5. Main switch
6. Section thickness knob
7. Motor box

  

8. Blade holder
9. Buffer tray
10. Magnifier assembly with fluorescent lamp
11. Up switch
12. Down switch
13. Retraction switch

Ordering Information
Prod #DescriptionUnitPriceOrder / Quote
10111
Microslicer™ DTK-Zero 1, 115V, 50/60Hz
each
P.O.R.
Qty:
10111-220
Microslicer™ DTK-Zero 1, 220V, 50/60Hz
each
P.O.R.
Qty:




Microslicer™ DTK-3000W

Microslicer™ DTK-3000W

70 x 70mm maximum specimen size
This is the most sophisticated model. The maximum specimen size is 70 x 70mm, in addition to having all the excellent features of the model DTK-Zero 1.

Functions Include:
Fully automatic single or continuous mode. Selection of section thickness is possible at one micron units with a high performance stepping motor for specimen advance. Equipped with a specimen retraction system. Forward and reverse blade movements are selectable at 1mm intervals.

  Functions Include:
 

1. Frequency dial
2. Cutting speed dial
3. Operation panel
4. Display (thickness)
5. Display (sectioning range)

  

6. Motor box
5. Blade holder
6. Buffer tray
7. Magnifier assembly with fluorescent lamp

Ordering Information
Prod #DescriptionUnitPriceOrder / Quote
10150
Microslicer™ DTK-3000W, 115V, 50/60Hz
each
P.O.R.
Qty:
10150-220
Microslicer™ DTK-3000W, 220V, 50/60Hz
each
P.O.R.
Qty:




LinearSlicer™ PRO7


LinearSlicer Left Panel LinearSlicer PRO7 LinearSlicer PRO7 right panel
Left Panel LinearSlicer™ PRO7 Right Panel


LinearSlicer™ PRO7

I. Intended Use of the Instrument
The LinearSlicer™ has been developed to cut slices from animal or plant tissues (fresh or chemically fixed) without the need to freeze them. In the bioscience research fields such as physiology, neuroscience and pharmacology, experiments are often conducted using fresh tissue slices. For example, fresh tissue slices from various parts of the brain are often used for the slice-patch method, blind-patch method, slice culture method and for the determination of calcium, etc.
The success in such experiments often depends on the quality of the tissue slices such as consistency of the thickness of the slices and integrity of preservation of nerve structures in the tissue slices. It was not always easy to obtain high quality tissue slices using conventional tissue slicers because these instruments have often shown significant loss of performance after long-term use.
The LinearSlicer™ has a linear motor system in the blade-shuttling mechanism that overcomes various difficulties in slicing fresh tissues. It has overcome the loss of performance after long-term use by removing all the wearing parts from the blade shuttling mechanism. Every researcher can obtain high quality fresh tissue slices with minimum damage to live cells with the LinearSlicer™

 LinearSlicer aerial view
LinearSlicer™ PRO7

II. General description and characteristics of the instrument.

1. The LinearSlicer™ does not use the outdated blade-shuttling mechanisms such as the magnetic vibration system that easily generates abnormal vibration, or the motor and cam-shaft system that usually shows loss of performance after long-term use. The LinearSlicer™ has a blade-shuttling mechanism that is equipped with a unique linear motor system developed by DOSAKA (patent pending). Because of this new technology, the LinearSlicer™ can produce thinner fresh tissue slices with less damage and have a much longer run life.

2. The width of the blade shuttling is constant with conventional tissue slicers but with the LinearSlicer™ the width of the blade shuttling is variable from 0-2mm. You can select the best shuttling width, adjusting to the characteristics of various tissues. The frequency of the blade shuttling is also variable from 50-100Hz.
At the electric resonance frequency (the frequency that the maximal horizontal vibration is obtained with the minimum electric frequency, 84 to 86Hz), the vertical deviation of the blade is minimum and less than 2µm. This performance is far superior to that of the conventional tissue slicers.
The frequency of blade shuttling is shown on the digital number display and you can record the best cutting frequency in your experiment for each kind of tissue and re-use the information for your next experiment.

3. The simplification of set up and movement of the specimen tray provides the speed necessary for cutting slices from fresh, raw tissues.


Prod #DescriptionUnitPriceOrder / Quote
10160
LinearSlicer PRO7, 115V, 50/60Hz
each
P.O.R.
Qty:
10160-230
LinearSlicer PRO7, 220V, 50/60Hz
each
P.O.R.
Qty:


Microslicer™ Specifications Overview
 Model  Prod. No.
10000 and 10000-220
Microslicer™
DTK-1000		 Prod. No.
10111 and 10111-220
Microslicer™
Zero 1		  Prod. No.
10150 and 10150-220
Microslicer™
DTK-3000W		  Prod. No.
10160 and 10160-220
LinearSlicer™ PRO7
Electrical 100/120/220/340, 50/60Hz 100/120/220/340, 50/60Hz 100/120/220/340, 50/60Hz 100/120/220/340, 50/60Hz
Blade Oscillating Frequency 0~55Hz 0~55Hz 0~55Hz 50-100Hz
Blade Oscillating Width 2mm fixed 2mm fixed 2mm fixed 0-2mm
Cutting Speed  0-68/mm/min. (about) 0-68/mm/min (about) 0-90/mm/min (about) 0-14mm/min.
Reverse Speed 104mm/min. (about) 104mm/min. (about) 104mm/min. (about) 22mm/min.
Maximum Specimen Height 20mm 20mm 20mm 10mm
Specimen Retraction Function no yes yes yes
Maximum Specimen Size 25x30mm 25x30mm 70x70mm 35x25x10mm H
Specimen Advance Manual Motorized Motorized/Automatic Motorized
Blade Holder Size For 30mm blade For 30mm blade For 30 or 70mm blade For 30mm blade
Automatic Operation no no yes Semi Automatic

retraction mechanism

The retraction mechanism is a function included in the DTK-Zero1 and DTK-3000W models that prevents the retracting blade from touching the face of the specimen. The specimen tray is lowered by 120 micrometers after the cutting of each section and is raised by exactly the same distance when a new cutting cycle starts.


Microslicer™ Accessories and Consumables

Microslicer™ Blade Holder

Microslicer™ Blade Holder

Black nylon and stainless steel

Prod #DescriptionUnitPriceOrder / Quote
10110-20B
Microslicer™ Blade Holder
each
$363.50
Qty:


tool for microslicer blade exchange

Tool for Microslicer™ Blade Exchange

Prod #DescriptionUnitPriceOrder / Quote
10112
Tool for Microslicer™ Blade Exchange
each
$22.35
Qty:

Microslicer™ Specimen Trays

Microslicer Specimen Tray Inside dimensions:
76 x 55 x 9.5mm
(3 x 2-3/16 x 3/8")

Prod #DescriptionUnitPriceOrder / Quote
10113
Microslicer™ Specimen Tray
each
$295.00
Qty:


stainless steel Microslicer Specimen Tray Stainless Steel
Inside dimensions:
74 x 55 x 12.7mm
(2.91 x 2-3/16 x 1/2")

Prod #DescriptionUnitPriceOrder / Quote
101-40M
Microslicer® Specimen Tray and Adapter, stainless steel
each
$97.25
Qty:


Microslicer Specimen Tray, black anodized aluminum Black Anodized Aluminum
Inside dimensions:
74 x 55 x 12.7mm
(2.91 x 2-3/16 x 1/2")

Prod #DescriptionUnitPriceOrder / Quote
101-42M
Microslicer™ Specimen Tray and Vise Adapter, black anodized aluminum
each
$69.50
Qty:
101-42
Vibratome® Specimen Tray and Vise Adapter, black anodized aluminum
each
49.50
Qty:


Feather® Blades

Feather® Blades

Double edge, carbon steel blade

Sharp edges; may be broken in half lengthwise (protect fingers and use eye protection).
This is the preferred razor blade for use with the Microslicer® and other vibrating microtomes.
• Length: 42.8mm (1.685");
• Cutting Edge Length: 36mm (1.42")
• Width: 22mm (.865")
• Thickness: .127mm (.005")

Prod #DescriptionUnitPriceOrder / Quote
121-9
Feather® Double edge, carbon steel blade
pkg/10
$8.45
Qty:


double edge, PTFE coated razor blades

Double Edge, Breakable Style Razor Blades

Double edge, stainless steel blade

PTFE-Coated stainless steel, individually wrapped and bulk packed.
Suitable blade for Microslicer™ and other brands of vibrating microtomes.
• Length: 42.9mm (1.69");
• Cutting Edge Length: 37.1mm (1.46")
• Width: 21.7mm (.855")
• Thickness: .11mm (.004")

Prod #DescriptionUnitPriceOrder / Quote
121-6
Double Edge Stainless Steel Razor Blades
box/250
$43.25
Qty:


Replacement bulb for Microslicers

Replacement Twin Bulb

for Microslicer™ Models 1000 and 1500E

Prod #DescriptionUnitPriceOrder / Quote
10174
Replacement, Twin Bulb for Microslicer® models 1000 and 1500E
each
$96.70
Qty:

 

Tissue-Tek® Accu-Edge® High and Low Profile Disposable Blades
accu-edge microtome blades
  • Reliably sharp, uniformly consistent
  • Ultrasharp edges with PTFE resin coating
  • Obtain acceptable ribbons sooner
  • Increase quality sections
  • Low profile for sections less than 3µm
  • High profile for tough material and sections over 3µm

For Sale in U.S.A. Only

Prod #DescriptionUnitPriceOrder / Quote
For Sale in U.S.A. Only
27235
Accu-Edge® 4689 Low Profile Blades, Dispenser of 50 blades, 80Lx8.31Wx0.26mmT (3.15"Lx.327"Wx.01"T)
each
$121.50
Qty:
27236
Tissue-Tek® Feather® 4980 Low Profile Blades, Dispenser of 50 blades, 80Lx8Wx0.24mmT (3.15"Lx.315"Wx.009"T)
each
223.80
Qty:
27237
Accu-Edge® 4685 High Profile Blades, Dispenser of 50 blades, 75.7Lx14Wx0.31mmT (2.98"Lx.55"Wx.012"T)
each
119.80
Qty:

 

DuraEdge™ Microtome Blades

PTFE coated, Low and High Profile blades

  • High quality hardened stainless steel finely honed and polished for flaw-free edge.
  • Special proprietary process ensures edge quality and promotes durability.
  • Uniform PTFE coating reduces friction, eliminates striations and compressions, and requires no break-in period.
  • Economy High Profile blades.
  • Ceramic coated, eliminating edge corrosion and enhancing product life.

Economy High Profile blades
Ceramic coated, eliminating edge corrosion and enhancing product life.

Prod #DescriptionUnitPriceOrder / Quote
27239
DuraEdge® 7221 Low Profile disposable Microtome Blades, PTFE coated, 77Lx8Wx.3mmT (3"Lx.315"Wx.012"T), Dispenser of 50 blades
each
$106.50
Qty:
27241
DuraEdge® 7310 High Profile disposable Microtome Blades, PTFE coated, 77Lx14Wx.3mmT (3"Lx.55"Wx.012"T), Dispenser of 50 blades
each
106.50
Qty:
27243
DuraEdge® 7203 High Profile disposable Microtome Blades, ceramic coated, economy blades, 77Lx14Wx.3mmT (3"Lx.55"Wx.012"T), Dispenser of 50 blades
each
104.60
Qty:



PTFE coated, stainless steel, injector razor blades

Injector Style Stainless Steel, PTFE-Coated Blades

Useful for Microslicer® and other vibrating microtomes. Single edge, 20 per dispenser.
• Length: 38.1mm (1.5");
• Cutting Edge Length: 36.3mm (1.43")
• Width: 8mm (.314")
• Thickness: .25mm (.010")

Prod #DescriptionUnitPriceOrder / Quote
121-4
Injector Blades, 20 blades in dispenser
each
$4.60
Qty:


PELCO Pro CA44 Tissue Adhesive

PELCO® Pro CA44 Tissue Adhesive

PELCO® Pro CA44 is an instant tissue adhesive based on cyanoacrylate. Developed to glue tissue on specimen holders used in vibrating microtomes, such Microslicer and Vibratome. Although the tissue adhesive is instable in boiling water, it is recommended to use #19920 PELCO® Pro Cyanoacrylate Debonder (below) to remove or clean cured cyanoacrylate. Supplied in 20ml bottle with dispenser tip, closed with ptfe coated steel pin for optimum seal.
Compatible to Loctite 404 tissue adhesive.
I - MSDS

Prod #DescriptionUnitPriceOrder / Quote
10033
PELCO® Pro CA44 Instant Tissue Adhesive, 20ml
each
$9.60
Qty:

The shelf life of cyanoacrylate glues (and epoxies) can be extended by storing them at lower temperatures; -20°C. At lower temperatures, the adhesive becomes very viscous and the speed of chemical reactions is practically reduced to zero. It will keep the adhesive stable for years. Before use, let the adhesive thaw with the container sealed to avoid condensation into the adhesive.

PELCO Cyanoacrylate Debonder

PELCO® Pro Cyanoacrylate Debonder

The PELCO® Pro Cyanoacrylate Debonder destabilizes and debonds cured cyanoacrylates. Useful for releasing specimens from holders, cleaning cyanoacrylates from surfaces and removing cured cyanoacylates from fingers. Works on all brands of cyanoacrylate glue (Loctite, Henkel, Permabond, 3M™, PELCO®, Aron Alpha, etc.). The debonder is also a solvent, please check before using on plastic surfaces / samples and avoid repeated skin contact. Supplied in 20ml bottle with dispenser tip.
F, Cg, I, T - MSDS - There are Hazard Shipping Fees associated with this product. Hazard Shipping Fees

Prod #DescriptionUnitPriceOrder / Quote
19920
PELCO® Pro Cyanoacrylate Debonder, 20ml
each
$5.69
Qty:


Locktite Quick-set

Loctite® 404 Quick-Set Tissue Adhesive

Microslicer™ applications and other quick-set tissue-slide uses.
0.33 oz. / 9.3g / 10ml
MSDS

Prod #DescriptionUnitPriceOrder / Quote
10035
Loctite® 404 Tissue Adhesive, 10ml
each
$31.25
Qty:


Specimen Retrievers

PELCO® Pro Specimen Retrievers

This is a perfect tool for retrieving free floating sections from the bath. Made of glass.

Prod #DescriptionUnitPriceOrder / Quote
101-33
PELCO® Pro Specimen Retrievers
pkg/5
$24.50
Qty:

Blades for Vibratomes and Microslicers


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Page Last Updated: February 10, 2012