The DTK Microslicers™ have a unique design for the vibratory motion of the cutting blade. They are made to cut
sections of extremely soft tissues like brain, liver or similar difficult-to-section material. The Microslicers™
line of instruments are well known for their quality and their superior results, enjoying an excellent reputation in
the neuroscience research community.
Objective of the Microslicer™
The Microslicer™ is an instrument used to cut sections of fresh or fixed animal or plant tissues without
freezing the tissues.
Fresh tissue sections (10 to 500 micrometers in thickness) are used in anatomy, physiology and pharmacology
research areas. In addition, fresh botanical tissue sections are also used in the various research fields.
Histochemistry and cytochemistry procedures require incubation of tissue sections in various reaction media.
Large tissue blocks and thick tissue sections often produce non-specific deposits of reaction products and areas
of no reaction in the center of the tissues. This is due to the poor penetration of the reaction media into the
tissue. The use of thinner tissue sections is required to facilitate the penetration of the reaction medium into
the tissues.
DSK Microslicer™ (DTK-1000, DTK-Zero1 and DTK-3000W) are instruments for cutting non-frozen tissue sections
easily and efficiently.
There is a Choice of Three Microslicer™ Models and the New LinearSlicer™ PRO7:
- Microslicer™ DTK-1000 - the basic model for manual operation
- Microslicer™ DTK-Zero1 - reduced Z-axis movement of the head for superior cutting quality, manual
unit but includes motorized specimen movement and features the useful retraction mode
- Microslicer™ DTK-3000W - automatic system for serial sectioning and includes the
Microslicer Zero Z technology.
- LinearSlicer™ PRO7 - the new and unique linear motor system developed by DOSAKA.
Produce thinner fresh tissue slices with less damage and have a much longer run life
(see below).
The Microslicer™ vibratory tissue slicer system feature a constant cutting amplitude and a selectable
frequency. The DTK-Zero1, and DTK-3000W models feature the Microslicer™ Zero-Z technology with a redesigned
cutting head for dramatically reduced Z-axis vibration. All systems have a bath with a simple but effective drain.
The specimen tray allow for reduced use of solutions and cooling around it. The layout of the switches on either
side of the tray allows for easy operation and reduced spillage on the controls.
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Microslicer™ DTK-1000
A high quality, basic vibratory microtome, suitable for a busy laboratory, with many users.
Functions Include:
- Frequency dial
- Cutting speed dial
- Function switch; reverse; stop; forward
- Lamp switch
- Main switch
- Section thickness knob
- Motor box
- Blade holder
- Buffer tray
- Magnifier assembly with fluorescent lamp
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Ordering Information
| Prod #
| Description
| Unit
| Price
| Order / Quote
|
10000
| Microslicer™ DTK-1000, 120V, 60Hz
| each
| P.O.R.
|
|
| 10000-220
| Microslicer™ DTK-1000, 220V, 50/60Hz
| each
| P.O.R.
|
|
|
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New Microslicer™ DTK-Zero1
the first tissue sectioning equipment with Zero "Z" technology
This model Microslicer™ with Zero Z technology dramatically reduces the Z-axis vibrations
to approximately 2.5 microns. It is also equipped with a specimen retraction system. The specimen
advance is manual but the specimen can be moved up or down by a motorized button. A function switch
can stop, advance or retract the cutting action, saving valuable time.
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Functions Include:
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1. Frequency dial
2. Cutting speed dial
3. Function switch; reverse; stop; forward
4. Lamp switch
5. Main switch
6. Section thickness knob
7. Motor box
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8. Blade holder
9. Buffer tray
10. Magnifier assembly with fluorescent lamp
11. Up switch
12. Down switch
13. Retraction switch
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Ordering Information
| Prod #
| Description
| Unit
| Price
| Order / Quote
|
10111
| Microslicer™ DTK-Zero 1, 115V, 50/60Hz
| each
| P.O.R.
|
|
| 10111-220
| Microslicer™ DTK-Zero 1, 220V, 50/60Hz
| each
| P.O.R.
|
|
|
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Microslicer™ DTK-3000W
70 x 70mm maximum specimen size
This is the most sophisticated model. The maximum specimen size is 70 x 70mm, in addition to having all
the excellent features of the model DTK-Zero 1.
Functions Include:
Fully automatic single or continuous mode. Selection of section thickness is possible at one micron units
with a high performance stepping motor for specimen advance. Equipped with a specimen retraction system.
Forward and reverse blade movements are selectable at 1mm intervals.
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Functions Include:
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1. Frequency dial
2. Cutting speed dial
3. Operation panel
4. Display (thickness)
5. Display (sectioning range)
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6. Motor box
5. Blade holder
6. Buffer tray
7. Magnifier assembly with fluorescent lamp
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Ordering Information
| Prod #
| Description
| Unit
| Price
| Order / Quote
|
10150
| Microslicer™ DTK-3000W, 115V, 50/60Hz
| each
| P.O.R.
|
|
| 10150-220
| Microslicer™ DTK-3000W, 220V, 50/60Hz
| each
| P.O.R.
|
|
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LinearSlicer™ PRO7
I. Intended Use of the Instrument
The LinearSlicer™ has been developed to cut slices from animal or plant tissues (fresh or chemically fixed)
without the need to freeze them. In the bioscience research fields such as physiology, neuroscience and pharmacology,
experiments are often conducted using fresh tissue slices. For example, fresh tissue slices from various parts of the
brain are often used for the slice-patch method, blind-patch method, slice culture method and for the determination of
calcium, etc.
The success in such experiments often depends on the quality of the tissue slices such as consistency of the thickness
of the slices and integrity of preservation of nerve structures in the tissue slices. It was not always easy to obtain
high quality tissue slices using conventional tissue slicers because these instruments have often shown significant loss
of performance after long-term use.
The LinearSlicer™ has a linear motor system in the blade-shuttling mechanism that overcomes various difficulties in
slicing fresh tissues. It has overcome the loss of performance after long-term use by removing all the wearing parts from
the blade shuttling mechanism. Every researcher can obtain high quality fresh tissue slices with minimum damage to live cells
with the LinearSlicer™
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LinearSlicer™ PRO7 |
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II. General description and characteristics of the instrument.
1. The LinearSlicer™ does not use the outdated blade-shuttling mechanisms such as the magnetic vibratory system that easily generates abnormal vibration, or the motor and cam-shaft system that usually shows loss of performance after long-term use. The LinearSlicer™ has a blade-shuttling mechanism that is equipped with a unique linear motor system developed by DOSAKA (patent pending). Because of this new technology, the LinearSlicer™ can produce thinner fresh tissue slices with less damage and have a much longer run life.
2. The width of the blade shuttling is constant with conventional tissue slicers but with the LinearSlicer™ the width of the blade shuttling is variable from 0-2mm. You can select the best shuttling width, adjusting to the characteristics of various tissues. The frequency of the blade shuttling is also variable from 50-100Hz.
At the electric resonance frequency (the frequency that the maximal horizontal vibration is obtained with the minimum electric frequency, 84 to 86Hz), the vertical deviation of the blade is minimum and less than 2µm. This performance is far superior to that of the conventional tissue slicers.
The frequency of blade shuttling is shown on the digital number display and you can record the best cutting frequency in your experiment for each kind of tissue and re-use the information for your next experiment.
3. The simplification of set up and movement of the specimen tray provides the speed necessary for cutting slices from fresh, raw tissues.
| Prod #
| Description
| Unit
| Price
| Order / Quote
|
10160
| LinearSlicer PRO7, 115V, 2A, 50/60Hz
| each
| P.O.R.
|
|
| 10160-230
| LinearSlicer PRO7, 220V, 1A, 50/60Hz
| each
| P.O.R.
|
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Tissue-Tek® Accu-Edge®
High and Low Profile Disposable Blades
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- Reliably sharp, uniformly consistent
- Ultrasharp edges with PTFE resin coating
- Obtain acceptable ribbons sooner
- Increase quality sections
- Low profile for sections less than 3µm
- High profile for tough material and sections over 3µm
For Sale in U.S.A. Only
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| Prod #
| Description
| Unit
| Price
| Order / Quote
|
| For Sale in U.S.A. Only
|
27235
| Accu-Edge® 4689 Low Profile Blades, Dispenser of 50 blades, 80Lx8.31Wx0.26mmT (3.15"Lx.327"Wx.01"T)
| each
| $121.50
|
|
| 27236
| Tissue-Tek® Feather® 4980 Low Profile Blades, Dispenser of 50 blades, 80Lx8Wx0.24mmT (3.15"Lx.315"Wx.009"T)
| each
| 230.35
|
|
| 27237
| Accu-Edge® 4685 High Profile Blades, Dispenser of 50 blades, 75.7Lx14Wx0.31mmT (2.98"Lx.55"Wx.012"T)
| each
| 119.80
|
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DuraEdge™ Microtome Blades
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PTFE coated, Low and High Profile blades
- High quality hardened stainless steel finely honed and polished for flaw-free edge.
- Special proprietary process ensures edge quality and promotes durability.
- Uniform PTFE coating reduces friction, eliminates striations and compressions, and requires no break-in period.
Economy High Profile blades
Ceramic coated, eliminating edge corrosion and enhancing product life.
|
|
| Prod #
| Description
| Unit
| Price
| Order / Quote
|
27241
| DuraEdge® 7310 High Profile disposable Microtome Blades, PTFE coated, 77Lx14Wx.3mmT (3"Lx.55"Wx.012"T), Dispenser of 50 blades
| each
| $106.50
|
|
| 27243
| DuraEdge® 7203 High Profile disposable Microtome Blades, ceramic coated, economy blades, 77Lx14Wx.3mmT (3"Lx.55"Wx.012"T), Dispenser of 50 blades
| each
| 104.60
|
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